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Take Clarithromycin exactly as directed by your doctor. Do not take more or less than instructed by your doctor. Take Clarithromycin at regular intervals as instructed. Take it at the same time each day. Do not skip any doses. Continue to take it even when you feel better. You must complete the entire course of antibiotic. If you dont, the infection will not clear completely. If you have been given tablets, swallow them whole with plenty of water. You may take them with or without food. If you have been given extended-release tablets, take them together with food or immediately after a meal. Swallow them whole, do not cut, chew or crush these extended-release tablets. If you have been given an oral suspension, shake it well before use to ensure that the liquid is evenly mixed. Use the measuring spoon or cup provided to measure your dose. You may take it with or without food.